Description
TB-500 is a synthetic analogue of Thymosin Beta-4, a naturally occurring 43-amino acid protein found in virtually all human and animal cells. It is one of the most studied peptides in preclinical research, examined extensively for its role in actin regulation, cell migration, angiogenesis, and tissue repair signaling pathways.
Molecular Formula: C₂₁₂H₃₅₀N₅₆O₇₈S
Molecular Weight: 4,963.5 g/mol
CAS Number: 77591-33-4
Sequence Length: 43 amino acids
Form: Lyophilized powder
Vial Size: 3mL
Amount: 5mg
Purity: ≥99% (HPLC verified)
For research use only. Not intended for human or animal consumption.
COA
Third-party Certificate of Analysis available upon request. All batches are independently tested via HPLC and mass spectrometry to verify ≥99% purity prior to release.
Contact support@synpeptidesciences.com to request batch-specific COA documentation.
Storage
All SYN Sciences peptides are manufactured using the lyophilization (freeze-drying) process, ensuring stability during shipping for up to 3–4 months at room temperature.
Once reconstituted with bacteriostatic water, store refrigerated at 2–8°C (36–46°F) and use within 30 days.
For long-term storage (months to years), store lyophilized peptide in a freezer at -20°C to -80°C, away from light and moisture.
Keep all peptides away from direct sunlight and repeated freeze-thaw cycles.
Manufacturing Process
All SYN Sciences peptides are synthesized using Solid Phase Peptide Synthesis (SPPS) — the industry gold standard for research-grade peptide production.
Process overview:
– Amino acid chains assembled on solid resin support under controlled conditions
– Cleavage and deprotection performed using pharmaceutical-grade reagents
– Purified via high-performance liquid chromatography (HPLC) to ≥99% purity
– Identity confirmed by mass spectrometry (MS)
– Screened for heavy metals and endotoxins
– Lyophilized (freeze-dried) and nitrogen-sealed in sterile vials for maximum stability
Every batch undergoes independent third-party quality verification before release.
Research
TB-500 is among the most researched peptides in preclinical tissue repair and cellular regulation studies. Laboratory research applications include:
– Actin sequestration and cytoskeletal dynamics research
– Cell migration, proliferation, and differentiation modeling
– Angiogenesis and new blood vessel formation studies
– Cardiac tissue repair and myocardial research models
– Tendon, ligament, and connective tissue repair studies
– Anti-inflammatory signaling pathway research
– Wound healing and extracellular matrix remodeling models
All references to biological activity are provided for scientific context only and do not constitute claims of therapeutic benefit. This product is not approved for human or animal use.
