Description
5-Amino 1MQ (5-Amino-1-methylquinolinium) is a small molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme involved in NAD+ metabolism and methylation reactions. It is studied in preclinical research for its role in cellular metabolism regulation, adipogenesis pathways, and SIRT1 activity modeling.
Molecular Formula: C₁₀H₁₁N₂⁺
Molecular Weight: 159.21 g/mol
CAS Number: 62687-40-5
Target Enzyme: Nicotinamide N-methyltransferase (NNMT)
Form: Lyophilized powder
Vial Size: 3mL
Amount: 5mg
Purity: ≥99% (HPLC verified)
For research use only. Not intended for human or animal consumption.
COA
Third-party Certificate of Analysis available upon request. All batches are independently tested via HPLC and mass spectrometry to verify ≥99% purity prior to release.
Contact support@synpeptidesciences.com to request batch-specific COA documentation.
Storage
All SYN Sciences peptides are manufactured using the lyophilization (freeze-drying) process, ensuring stability during shipping for up to 3–4 months at room temperature.
Once reconstituted with bacteriostatic water, store refrigerated at 2–8°C (36–46°F) and use within 30 days.
For long-term storage (months to years), store lyophilized peptide in a freezer at -20°C to -80°C, away from light and moisture.
Keep all peptides away from direct sunlight and repeated freeze-thaw cycles.
Manufacturing Process
All SYN Sciences peptides are synthesized using Solid Phase Peptide Synthesis (SPPS) — the industry gold standard for research-grade peptide production.
Process overview:
– Amino acid chains assembled on solid resin support under controlled conditions
– Cleavage and deprotection performed using pharmaceutical-grade reagents
– Purified via high-performance liquid chromatography (HPLC) to ≥99% purity
– Identity confirmed by mass spectrometry (MS)
– Screened for heavy metals and endotoxins
– Lyophilized (freeze-dried) and nitrogen-sealed in sterile vials for maximum stability
Every batch undergoes independent third-party quality verification before release.
Research
5-Amino 1MQ is studied in laboratory research settings for its role in NNMT inhibition and cellular metabolism regulation. Research applications include:
– Nicotinamide N-methyltransferase (NNMT) inhibition studies
– NAD+ metabolism and methylation pathway research
– Adipocyte differentiation and adipogenesis modeling
– SIRT1 pathway activation and regulation studies
– Intracellular NAD+ level modulation research
– Metabolic syndrome pathway modeling
– Small molecule NNMT inhibitor pharmacokinetic studies
All references to biological activity are provided for scientific context only and do not constitute claims of therapeutic benefit. This product is not approved for human or animal use.
