Description
PT-141 (Bremelanotide) is a synthetic peptide analogue of alpha-melanocyte stimulating hormone (α-MSH), developed from the melanocortin peptide Melanotan II. It acts as a melanocortin receptor agonist and is studied in laboratory research for its role in melanocortin signaling pathways and central nervous system receptor activation.
Molecular Formula: C₅₀H₆₈N₁₄O₁₀
Molecular Weight: 1025.17 g/mol
CAS Number: 189691-06-3
Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH
Sequence Length: 7 amino acids (cyclic)
Form: Lyophilized powder
Vial Size: 3mL
Amount: 10mg
Purity: ≥99% (HPLC verified)
For research use only. Not intended for human or animal consumption.
COA
Third-party Certificate of Analysis available upon request. All batches are independently tested via HPLC and mass spectrometry to verify ≥99% purity prior to release.
Contact support@synpeptidesciences.com to request batch-specific COA documentation.
Storage
All SYN Sciences peptides are manufactured using the lyophilization (freeze-drying) process, ensuring stability during shipping for up to 3–4 months at room temperature.
Once reconstituted with bacteriostatic water, store refrigerated at 2–8°C (36–46°F) and use within 30 days.
For long-term storage (months to years), store lyophilized peptide in a freezer at -20°C to -80°C, away from light and moisture.
Keep all peptides away from direct sunlight and repeated freeze-thaw cycles.
Manufacturing Process
All SYN Sciences peptides are synthesized using Solid Phase Peptide Synthesis (SPPS) — the industry gold standard for research-grade peptide production.
Process overview:
– Amino acid chains assembled on solid resin support under controlled conditions
– Cleavage and deprotection performed using pharmaceutical-grade reagents
– Purified via high-performance liquid chromatography (HPLC) to ≥99% purity
– Identity confirmed by mass spectrometry (MS)
– Screened for heavy metals and endotoxins
– Lyophilized (freeze-dried) and nitrogen-sealed in sterile vials for maximum stability
Every batch undergoes independent third-party quality verification before release.
Research
PT-141 is studied in laboratory research settings for its role in melanocortin receptor signaling and central nervous system pathway modeling. Research applications include:
– Melanocortin receptor (MC1R, MC3R, MC4R) binding and activation studies
– Central nervous system melanocortin signaling pathway research
– Hypothalamic pathway activation modeling
– Alpha-MSH analogue behavior and receptor selectivity studies
– Cyclic peptide stability and pharmacokinetic research
– Autonomic nervous system response modeling
– Melanocortin system regulation research
All references to biological activity are provided for scientific context only and do not constitute claims of therapeutic benefit. This product is not approved for human or animal use.
