Description
Melanotan II (MT-2) is a synthetic analogue of alpha-melanocyte stimulating hormone (α-MSH), a naturally occurring peptide derived from pro-opiomelanocortin (POMC). It is a cyclic heptapeptide studied in laboratory research for its role in melanocortin receptor activation, pigmentation pathway regulation, and central nervous system signaling studies.
Molecular Formula: C₅₀H₆₉N₁₅O₉
Molecular Weight: 1024.18 g/mol
CAS Number: 121062-08-6
Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH₂
Sequence Length: 7 amino acids (cyclic)
Form: Lyophilized powder
Vial Size: 3mL
Amount: 10mg
Purity: ≥99% (HPLC verified)
For research use only. Not intended for human or animal consumption.
COA
Third-party Certificate of Analysis available upon request. All batches are independently tested via HPLC and mass spectrometry to verify ≥99% purity prior to release.
Contact support@synpeptidesciences.com to request batch-specific COA documentation.
Storage
All SYN Sciences peptides are manufactured using the lyophilization (freeze-drying) process, ensuring stability during shipping for up to 3–4 months at room temperature.
Once reconstituted with bacteriostatic water, store refrigerated at 2–8°C (36–46°F) and use within 30 days.
For long-term storage (months to years), store lyophilized peptide in a freezer at -20°C to -80°C, away from light and moisture.
Keep all peptides away from direct sunlight and repeated freeze-thaw cycles.
Manufacturing Process
All SYN Sciences peptides are synthesized using Solid Phase Peptide Synthesis (SPPS) — the industry gold standard for research-grade peptide production.
Process overview:
– Amino acid chains assembled on solid resin support under controlled conditions
– Cleavage and deprotection performed using pharmaceutical-grade reagents
– Purified via high-performance liquid chromatography (HPLC) to ≥99% purity
– Identity confirmed by mass spectrometry (MS)
– Screened for heavy metals and endotoxins
– Lyophilized (freeze-dried) and nitrogen-sealed in sterile vials for maximum stability
Every batch undergoes independent third-party quality verification before release.
Research
Melanotan II is studied in laboratory research settings for its role in melanocortin receptor activation and pigmentation pathway modeling. Research applications include:
– Melanocortin receptor (MC1R, MC3R, MC4R, MC5R) binding studies
– Melanogenesis and skin pigmentation pathway research
– Alpha-MSH analogue receptor selectivity studies
– Central nervous system melanocortin signaling research
– Hypothalamic energy regulation pathway modeling
– Cyclic peptide pharmacokinetic and stability research
– Pro-opiomelanocortin (POMC) derived peptide behavior studies
All references to biological activity are provided for scientific context only and do not constitute claims of therapeutic benefit. This product is not approved for human or animal use.
